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Epigenomics and Mechanisms Branch (EGM)

Publications

All recent publications: 2024-2020

View Key Publications

  1. Al-Soneidar WA, Harper S, Coutlée F, Gheit T, Tommasino M, Nicolau B (2024). Prevalence of Alpha, Beta, and Gamma Human Papillomaviruses in Patients With Head and Neck Cancer and Noncancer Controls and Relation to Behavioral Factors. J Infect Dis. 229(4):1088–96. https://doi.org/10.1093/infdis/jiad335 PMID:37584283
  2. Berrington de González A, Masten SA, Bhatti P, Fortner RT, Peters S, Santonen T, et al. (2024). Advisory Group recommendations on priorities for the IARC Monographs. Lancet Oncol. 25(5):546–8. https://doi.org/10.1016/S1470-2045(24)00208-0 PMID:38621402
  3. Boni SP, Tenet V, Horo A, Heideman DAM, Bleeker MCG, Tanon A, et al.; on behalf The IeDEA West Africa Collaboration (2024). High-risk human papillomavirus distribution according to human immunodeficiency virus status among women with cervical cancer in Abidjan, Côte d’Ivoire, 2018 to 2020. Int J Cancer. 154(6):962–8. https://doi.org/10.1002/ijc.34774 PMID:37942579
  4. Choudhary P, Monasso GS, Karhunen V, Ronkainen J, Mancano G, Howe CG, et al. (2024). Maternal educational attainment in pregnancy and epigenome-wide DNA methylation changes in the offspring from birth until adolescence. Mol Psychiatry. 29(2):348–58. https://doi.org/10.1038/s41380-023-02331-5 PMID:38052982
  5. Chung F, Zavadil J (2024). New risk factors and molecular landscapes of hepatic angiosarcoma in the Taiwanese population†. J Pathol. 262(1):1–3. https://doi.org/10.1002/path.6224 PMID:37929656
  6. Dube Mandishora RS, Galati L, Reich RR, Combes JD, McKay-Chopin S, Makunike-Mutasa R, et al. (2024). Epstein-Barr Virus DNA Is Associated With Conjunctival Squamous Cell Carcinomas: A Case-Control Study From Zimbabwe. Open Forum Infect Dis. 11(4):ofae165. https://doi.org/10.1093/ofid/ofae165 PMID:38623569
  7. Gentile D, Chiummiento L, Santarsiere A, Funicello M, Lupattelli P, Rescifina A, et al. (2024). Targeting Viral and Cellular Cysteine Proteases for Treatment of New Variants of SARS-CoV-2. Viruses. 16(3):16. https://doi.org/10.3390/v16030338 PMID:38543704
  8. Li S, Spitz N, Ghantous A, Abrishamcar S, Reimann B, Marques I, et al. (2024). A Pregnancy and Childhood Epigenetics Consortium (PACE) meta-analysis highlights potential relationships between birth order and neonatal blood DNA methylation. Commun Biol. 7(1):66. https://doi.org/10.1038/s42003-023-05698-x PMID:38195839
  9. Maroui MA, Odongo GA, Mundo L, Manara F, Mure F, Fusil F, et al. (2024). Aflatoxin B1 and Epstein-Barr virus-induced CCL22 expression stimulates B cell infection. Proc Natl Acad Sci U S A. 121(16):e2314426121. https://doi.org/10.1073/pnas.2314426121 PMID:38574017
  10. Maroui MA, Odongo GA, Mundo L, Manara F, Mure F, Fusil F, et al. (2024). Aflatoxin B1 and Epstein-Barr virus-induced CCL22 expression stimulates B cell infection. Proc Natl Acad Sci U S A. 121(16):e2314426121. https://doi.org/10.1073/pnas.2314426121 PMID:38574017
  11. Ramadan F, Saab R, Ghamloush F, Khoueiry R, Herceg Z, Gomez L, et al. (2024). Exosome-Mediated Paracrine Signaling Unveils miR-1246 as a Driver of Aggressiveness in Fusion-Negative Rhabdomyosarcoma. Cancers (Basel). 16(9):1652. https://doi.org/10.3390/cancers16091652 PMID:38730605
  12. Ramasamy D, Thippannah M, Maharajan HRP, Balaiah M, Seshadri RA, Kodous AS, et al. (2024). Transcriptome-wide profiling identifies colon cancer-associated m6A transcripts and potential RNA methyl modifiers. Mol Biol Rep. 51(1):299. https://doi.org/10.1007/s11033-024-09217-x PMID:38345740
  13. Alfano R, Zugna D, Barros H, Bustamante M, Chatzi L, Ghantous A, et al. (2023). Cord blood epigenome-wide meta-analysis in six European-based child cohorts identifies signatures linked to rapid weight growth. BMC Med. 21(1):17. https://doi.org/10.1186/s12916-022-02685-7 PMID:36627699
  14. Alsadi N, Yasavoli-Sharahi H, Mueller R, Cuenin C, Chung F, Herceg Z, et al. (2023). Protective Mechanisms of Polyphenol-Enriched Blueberry Preparation in Preventing Inflammation in the Skin against UVB-Induced Damage in an Animal Model. Antioxidants (Basel). 13(1):19. https://doi.org/10.3390/antiox13010025 PMID:38275645
  15. Awada Z, Cahais V, Cuenin C, Akika R, Silva Almeida Vicente AL, Makki M, et al. (2023). Waterpipe and cigarette epigenome analysis reveals markers implicated in addiction and smoking type inference. Environ Int. 182:108260. https://doi.org/10.1016/j.envint.2023.108260 PMID:38006773
  16. Awuchi CG, Nwozo OS, Aja PM, Odongo GA (2023). High-pressure acidified steaming with varied citric acid dosing can successfully detoxify mycotoxins. Food Sci Nutr. 11(6):2677–85. https://doi.org/10.1002/fsn3.3324 PMID:37324899
  17. Chatterjee N, Sultana F, Roy R, Dey S, Naskar S, Dam A, et al. (2023). Prevalence of novel gamma HPV types 223 and 225 in oral cavity and skin of Indian normal and neoplastic participants. J Med Virol. 95(8):e29019. https://doi.org/10.1002/jmv.29019 PMID:37543989
  18. Chung FF, Maldonado SG, Nemc A, Bouaoun L, Cahais V, Cuenin C, et al. (2023). Buffy coat signatures of breast cancer risk in a prospective cohort study. Clin Epigenetics. 15(1):102. https://doi.org/10.1186/s13148-023-01509-6 PMID:37309009
  19. Criscuolo E, Pala F, Siracusano G, Venuti A (2023). Editorial: Viral escape of mucosal immunity in sexually transmitted diseases. Front Immunol. 14:1273515. https://doi.org/10.3389/fimmu.2023.1273515 PMID:37680623
  20. Feng X, Muller DC, Zahed H, Alcala K, Guida F, Smith-Byrne K, et al. (2023). Evaluation of pre-diagnostic blood protein measurements for predicting survival after lung cancer diagnosis. EBioMedicine. 92:104623. https://doi.org/10.1016/j.ebiom.2023.104623 PMID:37236058
  21. Gheit T, Muwonge R, Lucas E, Galati L, Anantharaman D, McKay-Chopin S, et al. (2023). Impact of HPV vaccination on HPV-related oral infections. Oral Oncol. 136:106244. https://doi.org/10.1016/j.oraloncology.2022.106244 PMID:36402055
  22. Gihbid A, El Amrani A, Mouh FZ, Gheit T, Benhessou M, Amrani M, et al. (2023). Prevalence of Polyomaviruses and Herpesviruses in Moroccan Breast Cancer. Pathogens. 12(5):640. https://doi.org/10.3390/pathogens12050640 PMID:37242310
  23. Giuliani E, Rollo F, Cota C, Gheit T, Galati L, McKay-Chopin S, et al. (2023). Alpha, Beta, and Gamma Human Papillomaviruses in Genital Lichen Sclerosus: A Retrospective Cross-Sectional Study. J Low Genit Tract Dis. 27(3):236–41. https://doi.org/10.1097/LGT.0000000000000741 PMID:37052458
  24. Gregório C, Thakur S, Camara Rivero R, Márcia Dos Santos Machado S, Cuenin C, Carreira C, et al. (2023). Telomere length assessment and molecular characterization of TERT gene promoter in periampullary carcinomas. Gene. 873:147460. https://doi.org/10.1016/j.gene.2023.147460 PMID:37150235
  25. Kadalayil L, Alam MZ, White CH, Ghantous A, Walton E, Gruzieva O, et al. (2023). Analysis of DNA methylation at birth and in childhood reveals changes associated with season of birth and latitude. Clin Epigenetics. 15(1):148. https://doi.org/10.1186/s13148-023-01542-5 PMID:37697338
  26. Karimi A, Jafari-Koshki T, Zehtabi M, Kargar F, Gheit T (2023). Predictive impact of human papillomavirus circulating tumor DNA in treatment response monitoring of HPV-associated cancers; a meta-analysis on recurrent event endpoints. Cancer Med. 12(17):17592–602. https://doi.org/10.1002/cam4.6377 PMID:37492996
  27. Kutz JM, Rausche P, Rasamoelina T, Ratefiarisoa S, Razafindrakoto R, Klein P, et al. (2023). Female genital schistosomiasis, human papilloma virus infection, and cervical cancer in rural Madagascar: a cross sectional study. Infect Dis Poverty. 12(1):89. https://doi.org/10.1186/s40249-023-01139-3 PMID:37749705
  28. Lozar T, Keske A, Dube Mandishora RS, Yu Q, Bailey A, Xu J, et al. (2023). Betapapillomaviruses in p16-Negative Vulvar Intraepithelial Lesions Associated with Squamous Cell Carcinoma. Viruses. 15(9):1950. https://doi.org/10.3390/v15091950 PMID:37766356
  29. Malagón T, Ribeiro AL, Montosa Nunes E, Gheit T, El-Zein M, Villa LL, et al. (2023). Betapapillomavirus natural history and co-detection with alphapapillomavirus in cervical samples of adult women. J Med Virol. 95(12):e29288. https://doi.org/10.1002/jmv.29288 PMID:38054528
  30. Mangiante L, Alcala N, Sexton-Oates A, Di Genova A, Gonzalez-Perez A, Khandekar A, et al. (2023). Multiomic analysis of malignant pleural mesothelioma identifies molecular axes and specialized tumor profiles driving intertumor heterogeneity. Nat Genet. 55(4):607–18. https://doi.org/10.1038/s41588-023-01321-1 PMID:36928603
  31. Massafra R, Fanizzi A, Amoroso N, Bove S, Comes MC, Pomarico D, et al. (2023). Analyzing breast cancer invasive disease event classification through explainable artificial intelligence. Front Med (Lausanne). 10:1116354. https://doi.org/10.3389/fmed.2023.1116354 PMID:36817766
  32. Mundo L, Leoncini L, Accardi-Gheit R (2023). Epstein-Barr Virus Infection in Cancer. Cancers (Basel). 15(18):7. https://doi.org/10.3390/cancers15184659 PMID:37760627
  33. Robertson SE, Yasukawa M, Marchion DC, Xiong Y, Naqvi SMH, Gheit T, et al. (2023). Prevalence of viral DNA in high-grade serous epithelial ovarian cancer and correlation with clinical outcomes. PLoS One. 18(12):e0294448. https://doi.org/10.1371/journal.pone.0294448 PMID:38039311
  34. Shahbazi R, Yasavoli-Sharahi H, Alsadi N, Sharifzad F, Fang S, Cuenin C, et al. (2023). Lentinula edodes Cultured Extract and Rouxiella badensis subsp. acadiensis (Canan SV-53) Intake Alleviates Immune Deregulation and Inflammation by Modulating Signaling Pathways and Epigenetic Mechanisms. Int J Mol Sci. 24(19):23. https://doi.org/10.3390/ijms241914610 PMID:37834058
  35. Shahbazi R, Yasavoli-Sharahi H, Mallet JF, Sharifzad F, Alsadi N, Cuenin C, et al. (2023). Novel Probiotic Bacterium Rouxiella badensis subsp. acadiensis (Canan SV-53) Modulates Gut Immunity through Epigenetic Mechanisms. Microorganisms. 11(10):19. https://doi.org/10.3390/microorganisms11102456 PMID:37894114
  36. Viguier M, Pérals C, Poirier B, Battistella M, Aubin F, Bachelez H, et al. (2023). Human papilloma virus-16-specific CD8+ T-cell expansions characterize different clinical forms of lichen planus and not lichen sclerosus et atrophicus. Exp Dermatol. 32(6):859–68. https://doi.org/10.1111/exd.14788 PMID:36922453
  37. Bertinazzi, M., Gheit, T., Polesel, J., McKay-Chopin, S., Cutrone, C., Sari, M., . . . Boscolo-Rizzo, P. (2022). Clinical implications of alpha, beta, and gamma HPV infection in juvenile onset recurrent respiratory papillomatosis. European Archives of Oto-Rhino-Laryngology. 279(1): 285-292. PMID: 34453571 https://doi.org/10.1007/s00405-021-07040-9    
  38. Boskovic, M., Roje, B., Chung, F. F., Gelemanovic, A., Cahais, V., Cuenin, C., . . . Terzic, J. (2022). DNA Methylome Changes of Muscle- and Neuronal-Related Processes Precede Bladder Cancer Invasiveness. Cancers. 14(3): 17. PMID: 35158756 https://doi.org/10.3390/cancers14030487        
  39. Cheikh, I. A., El-Baba, C., Youssef, A., Saliba, N. A., Ghantous, A., & Darwiche, N. (2022). Lessons learned from the discovery and development of the sesquiterpene lactones in cancer therapy and prevention. Expert Opin Drug Discov. 17(12): 1377-1405. PMID: 36373806 https://doi.org/10.1080/17460441.2023.2147920  
  40. Claeys, L., De Saeger, S., Scelo, G., Biessy, C., Casagrande, C., Nicolas, G., . . . Huybrechts, I. (2022). Mycotoxin Exposure and Renal Cell Carcinoma Risk: An Association Study in the EPIC European Cohort. Nutrients. 14(17): 3581. PMID: 36079840 https://doi.org/10.3390/nu14173581
  41. Das, S., Thakur, S., Korenjak, M., Sidorenko, V. S., Chung, F. F., & Zavadil, J. (2022). Aristolochic acid-associated cancers: a public health risk in need of global action. Nature Reviews: Cancer. 22(10): 576-591. PMID: 35854147 https://doi.org/10.1038/s41568-022-00494-x               
  42. de Andrade, K. C., Lee, E. E., Tookmanian, E. M., Kesserwan, C. A., Manfredi, J. J., Hatton, J. N., . . . Savage, S. A. (2022). The TP53 Database: transition from the International Agency for Research on Cancer to the US National Cancer Institute. Cell Death and Differentiation. 29(5): 1071-1073. PMID: 35352025 https://doi.org/10.1038/s41418-022-00976-3    
  43. Dona, M. G., Gheit, T., Chiantore, M. V., Vescio, M. F., Luzi, F., Rollo, F., . . . Di Bonito, P. (2022). Prevalence of 13 polyomaviruses in actinic keratosis and matched healthy skin samples of immunocompetent individuals. Infectious Agents and Cancer. 17(1): 59. PMID: 36457033 https://doi.org/10.1186/s13027-022-00472-w
  44. Dugue, P. A., Bodelon, C., Chung, F. F., Brewer, H. R., Ambatipudi, S., Sampson, J. N., . . . Southey, M. C. (2022). Methylation-based markers of aging and lifestyle-related factors and risk of breast cancer: a pooled analysis of four prospective studies. Breast Cancer Research. 24(1): 59. PMID: 36068634 https://doi.org/10.1186/s13058-022-01554-8     
  45. El Abiead, Y., Milford, M., Schoeny, H., Rusz, M., Salek, R. M., & Koellensperger, G. (2022). Power of mzRAPP-Based Performance Assessments in MS1-Based Nontargeted Feature Detection. Analytical Chemistry. 94(24): 8588-8595. PMID: 35671103 https://doi.org/10.1021/acs.analchem.1c05270
  46. Froment, P., Plotton, I., Giulivi, C., Fabre, S., Khoueiry, R., Mourad, N. I., . . . Dupont, J. (2022). At the crossroads of fertility and metabolism: the importance of AMPK-dependent signaling in female infertility associated with hyperandrogenism. Human Reproduction. 37(6): 1207-1228. PMID: 35459945 https://doi.org/10.1093/humrep/deac067          
  47. Galati, L., Chiocca, S., Duca, D., Tagliabue, M., Simoens, C., Gheit, T., . . . Tommasino, M. (2022). HPV and head and neck cancers: Towards early diagnosis and prevention. Tumour Virus Res. 14: 200245. PMID: 35973657 https://doi.org/10.1016/j.tvr.2022.200245          
  48. Galati, L., Combes, J. D., Le Calvez-Kelm, F., McKay-Chopin, S., Forey, N., Ratel, M., . . . Gheit, T. (2022). Detection of Circulating HPV16 DNA as a Biomarker for Cervical Cancer by a Bead-Based HPV Genotyping Assay. Microbiol Spectr. 10(2): e0148021. PMID: 35225653 https://doi.org/10.1128/spectrum.01480-21
  49. Gholap, D., Mhatre, S., Chaturvedi, P., Nair, S., Gheit, T., Tommasino, M., & Dikshit, R. (2022). Prevalence of human papillomavirus types in head and neck cancer sub-sites in the Indian population. Ecancermedicalscience. 16: 1358. PMID: 35510141 https://doi.org/10.3332/ecancer.2022.1358        
  50. Herceg, Z., Ghantous, A., & Chung, F. F.-L. (2022). Epigenetic Epidemiology of Cancer. In: K. B. Michels, editor.^editors. Epigenetic Epidemiology. ed. Cham: Springer International Publishing; pp. 325-342.         
  51. Karanovic, S., Ardin, M., Tang, Z., Tomic, K., Villar, S., Renard, C., . . . Zavadil, J. (2022). Molecular profiles and urinary biomarkers of upper tract urothelial carcinomas associated with aristolochic acid exposure. International Journal of Cancer. 150(2): 374-386. PMID: 34569060 https://doi.org/10.1002/ijc.33827  
  52. Karimi, A., Mohebbi, E., McKay-Chopin, S., Rashidian, H., Hadji, M., Peyghambari, V., . . . Zendehdel, K. (2022). Human Papillomavirus and Risk of Head and Neck Squamous Cell Carcinoma in Iran. Microbiol Spectr. 10(4): e0011722. PMID: 35708339 https://doi.org/10.1128/spectrum.00117-22             
  53. Manara, F., Jay, A., Odongo, G. A., Mure, F., Maroui, M. A., Diederichs, A., . . . Accardi, R. (2022). Epigenetic Alteration of the Cancer-Related Gene TGFBI in B Cells Infected with Epstein-Barr Virus and Exposed to Aflatoxin B1: Potential Role in Burkitt Lymphoma Development. Cancers. 14(5). PMID: 35267594 https://doi.org/10.3390/cancers14051284          
  54. Mena, M., Wang, X., Tous, S., Quiros, B., Clavero, O., Alejo, M., . . . Neck Cancer Study, G. (2022). Concordance of p16(INK4a) and E6*I mRNA among HPV-DNA-Positive Oropharyngeal, Laryngeal, and Oral Cavity Carcinomas from the ICO International Study. Cancers. 14(15): 12. PMID: 35954451 https://doi.org/10.3390/cancers14153787          
  55. Reimann, B., Martens, D. S., Wang, C., Ghantous, A., Herceg, Z., Plusquin, M., & Nawrot, T. S. (2022). Interrelationships and determinants of aging biomarkers in cord blood. Journal of Translational Medicine. 20(1): 353. PMID: 35945616 https://doi.org/10.1186/s12967-022-03541-1               
  56. Silver, M. J., Saffari, A., Kessler, N. J., Chandak, G. R., Fall, C. H. D., Issarapu, P., . . . Prentice, A. M. (2022). Environmentally sensitive hotspots in the methylome of the early human embryo. Elife. 11. PMID: 35188105 https://doi.org/10.7554/eLife.72031      
  57. Simoens, C., Gheit, T., Ridder, R., Gorbaslieva, I., Holzinger, D., Lucas, E., . . . group, H.-A. s. (2022). Accuracy of high-risk HPV DNA PCR, p16((INK4a)) immunohistochemistry or the combination of both to diagnose HPV-driven oropharyngeal cancer. BMC Infectious Diseases. 22(1): 676. PMID: 35933382 https://doi.org/10.1186/s12879-022-07654-2     
  58. Solomon, O., Huen, K., Yousefi, P., Kupers, L. K., Gonzalez, J. R., Suderman, M., . . . Holland, N. (2022). Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation. Mutat Res Rev Mutat Res. 789: 108415. PMID: 35690418 https://doi.org/10.1016/j.mrrev.2022.108415   
  59. Straub Hogan, M. M., Spieker, A. J., Orejudos, M., Gheit, T., Herfs, M., Tommasino, M., . . . Giannico, G. A. (2022). Pathological characterization and clinical outcome of penile intraepithelial neoplasia variants: a North American series. Modern Pathology. 35(8): 1101-1109. PMID: 35190664 https://doi.org/10.1038/s41379-022-01020-y              
  60. Talukdar, F. R., Abramovic, I., Cuenin, C., Carreira, C., Gangane, N., Sincic, N., & Herceg, Z. (2022). A protocol for good quality genomic DNA isolation from formalin-fixed paraffin-embedded tissues without using commercial kits. Molecular Biology Reports. 49(5): 4115-4121. PMID: 35359238 https://doi.org/10.1007/s11033-022-07394-1                
  61. Talukdar, F. R., Escobar Marcillo, D. I., Laskar, R. S., Novoloaca, A., Cuenin, C., Sbraccia, P., . . . Herceg, Z. (2022). Bariatric surgery-induced weight loss and associated genome-wide DNA-methylation alterations in obese individuals. Clinical Epigenetics. 14(1): 176. PMID: 36528638 https://doi.org/10.1186/s13148-022-01401-9                
  62. Thakur, S., Cahais, V., Turkova, T., Zikmund, T., Renard, C., Stopka, T., . . . Zavadil, J. (2022). Chromatin Remodeler Smarca5 Is Required for Cancer-Related Processes of Primary Cell Fitness and Immortalization. Cells. 11(5): 808. PMID: 35269430 https://doi.org/10.3390/cells11050808    
  63. Venuti, A., Romero-Medina, M. C., Melita, G., Ceraolo, M. G., Brancaccio, R. N., Sirand, C., . . . Tommasino, M. (2022). Lyon IARC Polyomavirus Displays Transforming Activities in Primary Human Cells. Journal of Virology. 96(14): e0206121. PMID: 35770990 https://doi.org/10.1128/jvi.02061-21            
  64. Vicente, A., Novoloaca, A., Cahais, V., Awada, Z., Cuenin, C., Spitz, N., . . . Ghantous, A. (2022). Cutaneous and acral melanoma cross-OMICs reveals prognostic cancer drivers associated with pathobiology and ultraviolet exposure. Nat Commun. 13(1): 4115. PMID: 35840550 https://doi.org/10.1038/s41467-022-31488-w      
  65. Vidican, P., Perol, O., Fevotte, J., Fort, E., Treilleux, I., Belladame, E., . . . Charbotel, B. (2022). Frequency of Asbestos Exposure and Histological Subtype of Ovarian Carcinoma. International Journal of Environmental Research and Public Health. 19(9): 5383. PMID: 35564776 https://doi.org/10.3390/ijerph19095383     
  66. Awada, Z., Bouaoun, L., Nasr, R., Tfayli, A., Cuenin, C., Akika, R., . . . Ghantous, A. (2021). LINE-1 methylation mediates the inverse association between body mass index and breast cancer risk: A pilot study in the Lebanese population. Environ Res. 197: 111094. PMID: 33839117  doi: 10.1016/j.envres.2021.111094
  67. Barupal, D. K., Schubauer-Berigan, M. K., Korenjak, M., Zavadil, J., & Guyton, K. Z. (2021). Prioritizing cancer hazard assessments for IARC Monographs using an integrated approach of database fusion and text mining. Environ Int. 156: 106624. PMID: 33984576  doi: 10.1016/j.envint.2021.106624
  68. Camuzi, D., Buexm, L. A., Lourenco, S. Q. C., Esposti, D. D., Cuenin, C., Lopes, M. S. A., . . . Soares-Lima, S. C. (2021). HPV Infection Leaves a DNA Methylation Signature in Oropharyngeal Cancer Affecting Both Coding Genes and Transposable Elements. Cancers (Basel). 13(14). PMID: 34298834  doi: 10.3390/cancers13143621
  69. Cree, I. A., Indave Ruiz, B. I., Zavadil, J., McKay, J., Olivier, M., Kozlakidis, Z., . . . participants, I. R. (2021). The International Collaboration for Cancer Classification and Research. Int J Cancer. 148(3): 560-571. PMID: 32818326  doi: 10.1002/ijc.33260
  70. Faure, M. C., Khoueiry, R., Quanico, J., Acloque, H., Guerquin, M. J., Bertoldo, M. J., . . . Froment, P. (2021). In Utero Exposure to Metformin Reduces the Fertility of Male Offspring in Adulthood. Front Endocrinol (Lausanne). 12: 750145. PMID: 34745014  doi: 10.3389/fendo.2021.750145
  71. Fortuno, C., Lee, K., Olivier, M., Pesaran, T., Mai, P. L., de Andrade, K. C., . . . ClinGen, T. P. V. C. E. P. (2021). Specifications of the ACMG/AMP variant interpretation guidelines for germline TP53 variants. Hum Mutat. 42(3): 223-236. PMID: 33300245  doi: 10.1002/humu.24152
  72. Ghantous, A., Novoloaca, A., Bouaoun, L., Cuenin, C., Cros, M. P., Xu, Y., . . . Routledge, M. N. (2021). Aflatoxin Exposure during Early Life Is Associated with Differential DNA Methylation in Two-Year-Old Gambian Children. Int J Mol Sci. 22(16). PMID: 34445674  doi: 10.3390/ijms22168967
  73. Giuliani, M., Gheit, T., Rollo, F., Tommasino, M., Latini, A., Benevolo, M., . . . Dona, M. G. (2021). Predictors of Oral Infection by Mucosal and Cutaneous Human Papillomaviruses in HIV-Infected and Uninfected Men Who Have Sex with Men of the OHMAR Study. J Clin Med. 10(13): 9. PMID: 34202235  doi: 10.3390/jcm10132804
  74. Jacobson, S., Dahlqvist, P., Johansson, M., Svensson, J., Billing, O., Sund, M., & Franklin, O. (2021). Hyperglycemia as a risk factor in pancreatic cancer: A nested case-control study using prediagnostic blood glucose levels. Pancreatology. 21(6): 1112-1118. PMID: 34049822  doi: 10.1016/j.pan.2021.05.008
  75. Karabegovic, I., Portilla-Fernandez, E., Li, Y., Ma, J., Maas, S. C. E., Sun, D., . . . Ghanbari, M. (2021). Epigenome-wide association meta-analysis of DNA methylation with coffee and tea consumption. Nat Commun. 12(1): 2830. PMID: 33990564  doi: 10.1038/s41467-021-22752-6
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