Global attribution of HPV genotypes to invasive cervical cancer: a systematic analysis

A new systematic analysis by scientists from the International Agency for Research on Cancer (IARC) sheds light on the global impact of different human papillomavirus (HPV) genotypes in causing cervical cancer. The study, published today in The Lancet, is based on a novel methodology comparing HPV genotypes in more than 110 000 women with cervical cancer with those in more than 2.5 million cancer-free women (controls). It aimed to evaluate which HPV genotypes caused cancer as well as their carcinogenic strength and their contribution to the cervical cancer burden.

Wei F, Georges D, Man I, Baussano I, Clifford GM.
Causal attribution of human papillomavirus genotypes to invasive cervical cancer worldwide: a systematic analysis of the global literature
Lancet. Published online 1 August 2024;
https://doi.org/10.1016/S0140-6736(24)01097-3

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