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In a major step forward in the effort to eliminate cervical cancer in Europe, the Expert Working Group of the European Commission (EC) Initiative on Cervical Cancer (EC-CvC) has released its first set of recommendations for cervical cancer screening. The EC-CvC Expert Working Group recommends the use of human papillomavirus (HPV) detection testing as the primary screening method for asymptomatic populations with a cervix aged 30–64 years, with a conditional recommendation for screening starting at age 25 years using the same testing method.
This important milestone of the EC-CvC is part of a broader effort led by the Early Detection, Prevention, and Infections Branch at the International Agency for Research on Cancer (IARC) in collaboration with the EC’s Joint Research Centre (JRC). The EC-CvC aims to update cervical cancer screening guidelines to inform patients, health professionals, and policy-makers.
The EC-CvC Expert Working Group recommends against cervical cancer screening in asymptomatic populations with a cervix aged younger than 25 years and suggests not screening those aged 65 years or older unless they have never been screened or have not been screened in the past 10 years with HPV testing.
Cervical cytology and co-testing (cytology and HPV detection test) are not recommended as primary screening methods. Existing screening programmes that use these methods should transition to HPV-based screening, with an effective triage strategy in place for those who are HPV-positive, especially in younger populations. No new screening programmes based on cytology or co-testing as the primary screening method should be initiated.
