| Year | Degree | Major | Institution | Country/Town |
|---|---|---|---|---|
| 2005 | Ph.D | Molecular Epidemiology | University of Liege (ULg) | Belgium / Liege |
| 2001 | M.Sc | Engineering in Biology and Biochemistry | National Institute of Applied Sciences | France / Lyon |
| 1999 | B.Sc (Hons) | Biochemistry and Applied Biology | University of Caen, France | France / Caen |
Current Research Projects
Investigating the potential of TERT promoter mutations as a non-invasive biomarker for early detection and monitoring of urothelial cancer
F. Le Calvez-Kelm (PI), A. Manel, E. Vian, G. Scelo, MI Hosen, M. Zvereva, G. Byrnes, M. Sheikh, G. Durand, N. Forey, C. Voegele, S. Meziani, C. Jeronimo, E. Weiderpass, J. McKay, P. Brennan, R. Malekzadeh
Biology of cell-free DNA and enhancing their detection for cancer detection
F. Le Calvez-Kelm (PI), M. Zvereva, G. Scelo, G. Durand, C. Voegele, G. Byrnes, J. McKay
KRAS mutations in blood circulating cell-free DNA for the detection of pancreatic cancer
G. Scelo (PI), F. Le Calvez-Kelm (co-PI), G. Byrnes, M. Foll, G. Durand, S. Rinaldi, J. McKay, P. Brennan
Impact of weight loss on the mutational load of histological normal colorectal tissue
M Gunter (PI), G. Scelo, Muller D, F. Le Calvez-Kelm, C. Voegele, G. Durand
Development of the IARC Genetic Platform and coordination of research projects
F. Le Calvez-Kelm, and many collaborators
Selected Publications
Avogbe PH, Manel A, Vian E, Durand G, Forey N, Voegele C, Zvereva M, Hosen MI, Meziani S, De tilly B, Polo B, Lole O, Francois P, Tiffany Myriam Delhomme TM, Carreira C, Monteiro-Reis S, Henrique R, Abedi-Ardekani B, Byrnes G, Foll M, Weiderpass E, McKay J, Jeronimo C, Scelo G, Le Calvez-Kelm F. Urinary TERT promoter mutations as non-invasive biomarkers for the comprehensive detection of urothelial cancer 2019. EBioMedicine. In press, https://doi.org/10.1016/j.ebiom.2019.05.004
Scelo G, Purdue MP, Brown KM, Johansson M, Wang Z, Eckel-Passow JE, Ye Y, Hofmann JN, Choi J, Foll M, Gaborieau V, Machiela MJ, Colli LM, Li P, Sampson JN, Abedi-Ardekani B, Besse C, Blanche H, Boland A, Burdette L, Chabrier A, Durand G, Le Calvez-Kelm F, Prokhortchouk E, Robinot N, Skryabin KG, Wozniak MB, Yeager M, Basta-Jovanovic G, Dzamic Z, Foretova L, Holcatova I, Janout V, Mates D, Mukeriya A, Rascu S, Zaridze D, Bencko V, Cybulski C, Fabianova E, Jinga V, Lissowska J, Lubinski J, Navratilova M, Rudnai P, Szeszenia-Dabrowska N, Benhamou S, Cancel-Tassin G, Cussenot O, Baglietto L, Boeing H, Khaw KT, Weiderpass E, Ljungberg B, Sitaram RT, Bruinsma F, Jordan SJ, Severi G, Winship I, Hveem K, Vatten LJ, Fletcher T, Koppova K, Larsson SC, Wolk A, Banks RE, Selby PJ, Easton DF, Pharoah P, Andreotti G, Freeman LEB, Koutros S, Albanes D, Männistö S, Weinstein S, Clark PE, Edwards TL, Lipworth L, Gapstur SM, Stevens VL, Carol H, Freedman ML, Pomerantz MM, Cho E, Kraft P, Preston MA, Wilson KM, Michael Gaziano J, Sesso HD, Black A, Freedman ND, Huang WY, Anema JG, Kahnoski RJ, Lane BR, Noyes SL, Petillo D, Teh BT, Peters U, White E, Anderson GL, Johnson L, Luo J, Buring J, Lee IM, Chow WH, Moore LE, Wood C, Eisen T, Henrion M, Larkin J, Barman P, Leibovich BC, Choueiri TK, Mark Lathrop G, Rothman N, Deleuze JF, McKay JD, Parker AS, Wu X, Houlston RS, Brennan P, Chanock SJ. Genome-wide association study identifies multiple risk loci for renal cell carcinoma. Nat Commun. 2017 Jun 9; 8:15724
Fernandez-Cuesta L, Perdomo S, Avogbe PH, Leblay N, Delhomme TM, Gaborieau V, Abedi-Ardekani B, Chanudet E, Olivier M, Zaridze D, Mukeria A, Vilensky M, Holcatova I, Polesel J, Simonato L, Canova C, Lagiou P, Brambilla C, Brambilla E, Byrnes G, Scelo G, Le Calvez-Kelm F, Foll M, McKay JD, Brennan P. Identification of Circulating Tumor DNA for the Early Detection of Small-cell Lung Cancer. EBioMedicine. 2016 Aug; 10:117-23.
Le Calvez-Kelm F, Foll M, Wozniak MB, Delhomme TM, Durand G, Chopard P, Pertesi M, Fabianova E, Adamcakova Z, Holcatova I, Foretova L, Janout V, Vallee MP, Rinaldi S, Brennan P, McKay JD, Byrnes GB, Scelo G. KRAS mutations in blood circulating cell-free DNA: a pancreatic cancer case-control. Oncotarget. 2016 Nov 29;7(48) 78827-78840
Park DJ, Tao K, Le Calvez-Kelm F, Nguyen-Dumont T, Robinot N, Hammet F, Odefrey F, Tsimiklis H, Teo ZL, Thingholm LB, Young EL, Voegele C, Lonie A, Pope BJ, Roane TC, Bell R, Hu H, Shankaracharya, Huff CD, Ellis J, Li J, Makunin IV, John EM, Andrulis IL, Terry MB, Daly M, Buys SS, Snyder C, Lynch HT, Devilee P, Giles GG, Hopper JL, Feng BJ, Lesueur F, Tavtigian SV, Southey MC, Goldgar DE. Rare mutations in RINT1 predispose carriers to breast and Lynch syndrome-spectrum cancers. Cancer Discov. 2014 Jul;4(7) 804-15